The Venture Bros. (2003) series

The warped misadventures of a former boy genius turned washed-up, middle-aged mad scientist Dr. Rusty Venture; his moronic teenage sons; their maniac bodyguard; and the Doctor's arch-nemeses, incompetent super villain The Monarch and his masculine paramour, Dr. Girlfriend.
Genres: Sci-Fi / Comedy / Adventure / Action / Animation
Cast: Christopher McCulloch, James Urbaniak and Michael Sinterniklaas